Abstract—Alzheimer’s disease is a chronic progressive neurodegenerative disease, the pathogenesis of Alzheimer’s disease is still unclear, and individual etiological hypotheses cannot fully explain the emergence of a variety of complex pathological phenomena, the mainstream etiological hypotheses are three: central cholinergic system damage theory, Tua protein hyperphosphorylation and Aβ-amyloid hypothesis. The mainstay of treatment is now pharmacological. The mainstay of treatment is now pharmacological, and non-pharmacological therapies are gradually coming into the public eye. This research discusses the lack of optimism in drug development questions the mainstream theory, and argues that more emphasis should be placed on early prevention and intervention. 
 

Keywords—causes, Alzheimer’s disease, treatment, drugs, non-pharmaceutical 

Cite: Weilun Zhao, "The Direction and Future of Alzheimer’s Treatment," International Journal of Pharma Medicine and Biological Sciences, Vol. 14, No. 1, pp. 17-23, 2025.

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